Chloramphenicol Derivatives with Antibacterial Activity Identified by Functional Metagenomics
نویسندگان
چکیده
منابع مشابه
Novel florfenicol and chloramphenicol resistance gene discovered in Alaskan soil by using functional metagenomics.
Functional metagenomics was used to search for florfenicol resistance genes in libraries of cloned DNA isolated from Alaskan soil. A gene that mediated reduced susceptibility to florfenicol was identified and designated pexA. The predicted PexA protein showed a structure similar to that of efflux pumps of the major facilitator superfamily.
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ژورنال
عنوان ژورنال: Journal of Natural Products
سال: 2018
ISSN: 0163-3864,1520-6025
DOI: 10.1021/acs.jnatprod.7b00903